| Mouse (Mus
musculus)
Major Mouse Databases and Centers
Databases and Projects with Mouse Subsections
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GeneBank, NCBI:
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UniGene
is an experimental system for automatically partitioning GenBank sequences
into a non-redundant set of gene-oriented clusters. Each UniGene cluster
contains sequences that represent a unique gene, including ESTs, as well
as related information such as the tissue types in which the gene has been
expressed and map location.
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MGC Mammalian Gene Collection.
The goal of the MGC is to provide a complete set of full-length (open reading
frame) sequences and cDNA clones of expressed genes for human and
mouse.
The MGC is an NIH initiative that supports the production of cDNA libraries,
clones and sequences. All the resources generated by the MGC are publicly
accessible to the biomedical research community.
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euGenes, Genomic Information for Eukaryotic Organisms, Indiana University:
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MIT Center for Genome Research
at the Whitehead Institute:
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KEGG Kyoto Encyclopedia
of Genes and Genomes:
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Animal Genome Database, Japan:
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OMIA Online
Mendelian Inheritance in Animals
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GXD,
Gene Expression Information Resource Project, a collaborative effort
of The Jackson Laboratory, the MRC and University in Edinburgh, and associated
laboratories in North America and Europe.
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MTB,
Mouse Tumor Biology Database has been designed to aid researchers in
such areas as choosing experimental models, reviewing patterns of mutations
in specific cancers, and identifying genes that are commonly mutated across
a spectrum of cancers.
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Portable Dictionary
of the Mouse Genome University of Tenessee, US
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TIGR Mouse Gene Index
integrates research data from international mouse gene research projects.
The goal of this project is to ultimately represent a non-redundant view
of all mouse genes and data on their expression patterns, cellular roles,
functions, and evolutionary relationships.
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DHMHD, The Dysmorphic
Human-Mouse Homology Database consists of three separate databases
of human and mouse malformation syndromes together with a database of mouse/human
syntenic regions. The mouse and human malformation databases are linked
together through the chromosome synteny database. The purpose of the system
is to allow retrieval of syndromes according to detailed phenotypic descriptions
and to be able to carry out homology searches for the purpose of gene mapping.
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FANTOM is a collection
of functional annotations for the RIKEN full-length cDNA clones and provides
not simply the gene functions themselves, but also many other informative
and useful data describing functional information about the clones.
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RIKEN Mouse Encyclopedia
Genome Sequencing and Mapping
Projects
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Sequencing:
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Maps and Mapping:
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Maps and
Mapping Data at Jackson Laboratory
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Gene Map Data
Repository at UT Memphis
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BAC fingerprint
map of the mouse genome at BC Cancer Agency
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Mouse chromosome
5 annotation project, University of Pennslyvania.
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Genetic and
Physical Maps of the Mouse Genome, MIT
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Chromosome Correspondence
in the Linkage Map between mouse and human, pig, cattle
and rat
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Mouse Maps
from Animal Genome Database, Japan:
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RLGS, Restriction
Landmark Genomic Scanning, a genetic linkage map of a Japanese wild
mouse strain Mus musculus molossinus
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Mouse Physical
Mapping, from MGU at Harwell, UK
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Maps
of Mouse Imprinded Genes. The site contains data, chromosomal maps
and references relating to imprinted genes in the mouse and chromosome
regions with imprinting phenotypes, from MGU at Harwell, UK
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Comparative Maps:
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Radiation Hybrid Maps and Databases:
Atlases and Images
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MBL, Mouse Brain Library,
a collection of high-resolution histological images, atlases, MRIs, and
databases on brain structure of more than 100 strains of mice.
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2-dimensional Atlas of Mouse
Embryology, from MuriTech
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µMRI Atlas
of Mouse Development, A 3D digital atlas, Caltech
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The Visible Mouse, UC
Davis. This site is designed to introduce you to the Anatomy, Physiology,
Histology and Pathology of the Laboratory Mouse with an emphasis on Genetically
Engineered Mice.
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Mouse Atlas and Gene Expression
Database Project at The UK MRC Human Genetics Unit in Edinburgh
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The Virtual Mouse
Necropsy
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Guide to the Necropsy
of the Mouse, by Vincenzo Covelli
Mutagenesis/Transgenics/Knockouts
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My Mouse The
goal of mymouse.org is to facilitate international collaborative research
between phenotype screening centers and the mouse mutagenesis community,
and to promote interactions among scientists interested in analyzing the
biological mechanisms linking genes, function, and phenotypes.
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TBASE -- Transgenic/Targeted
Mutation Database, Jackson Laboratory
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Transgenic
and Targeted Mutant Animal Database, ORNL
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BigBlue
Website Transgenic rodents for the study of mutations in animals
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IMR
-- Induced Mutant Resources of the Jackson Laboratory
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ENU-Mouse
Mutagenesis Screen Project, by German Human Genome Project
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Mutabase - ENU
Mutagenesis Programme, hosted at the UK Mouse Genome Centre, Harwell
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GeneTrap, Systematic
Functional Analysis of Mammalian Genes Using Gene Trapping Approaches,
DHGP
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Mouse Knockout
& Mutation Database at BioMedNet
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UCD
Medpath Transgenic Mouse Searcher 2.0
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Database
of Gene Knockouts This gene knockout database is created at Frontiers
in Bioscience
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CMHD - Centre for Modeling
Human Disease, Toronto, Canada. The goal of the Certe is to produce
new mouse models of human disorders by extensive genome-wide random mutagenesis
and phenotypic screens.
Stocks, Mutants, and Reagents
see also Antibodies and Cell
Lines
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IMSR International
Mouse Strain Resources is a collaborative project between The
Jackson Laboratory, Bar Harbor, USA and the Medical Research Council
Mammalian Genetics Unit, Harwell, UK. It aims to give access to information
concerning animal strains over the internet.
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Mouse
Stocks at Harwell Mammalian Genetics Unit, MRC UK. Harwell's mouse
stocks contain a wide range of over 200 mutant, chromosome anomaly and
inbred lines. The stocks are maintained for experimental and breeding purposes,
and are available to investigators on request.
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JAX®
MICE Database Search
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EMMA, the European Mouse Mutant
Archive is a non-profit repository of the transgenic mouse lines. These
lines are available for the qualified research scientists.
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ENU Mutagenesis Programme
at the MRC Mammalian Genetics Unit, Harwell, is a large scale mouse genetics
programme to identify new phenotypes of relevance to human disease. The
programme will use high throughput screens devised by the consortium in
order to survey thousands of progeny of ENU treated mice each year and
identify those mice carrying novel phenotypes. Mice from the programme
will be available to outside investigators.
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ORNL Mutant Mouse Database
Oak Ridge National Laboratory has a collection of several hundred mouse
stocks, most of which propagate mutations induced by radiations or chemicals.
Stocks listed in this database exist as one or more of the following: (a)
live mice; (b) frozen embryos or sperm; and (c) selected frozen tissues.
Except in some cases where active work is in progress at ORNL, these materials
are available to outside investigators on special request.
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FESA,
the mouse Frozen Embryo and Sperm Archive facility at Harwell is one
of the largest in the world and contains almost 1,000 stocks. These are
available for recovery and supply as frozen embryos (some as frozen sperm)
or breeding nuclei.
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HUGO
Mutation Database Initiative Non-Human Variation Databases
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Mutation
Research Genomics Initiative
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NGRP National Genetic Resources
Program
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NAGP National Animal Germplasm
Program
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Transgenic
and Targeted Mutant Animal Database at the Oak Ridge National Laboratory
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CLDB, Cell
Line Data Base contains detailed information on 4.671 human and animal
cell lines that are available in many Italian laboratories and in some
of the most important European cell banks and cell culture collections.
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MAFF DNA bank at Ministry
of Agriculture, Forestry and Fisheries of Japan is responsible for the
preservation of DNA and molecular information on agricultual organisms.
This bank acts as a research support service.
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DISC, DNA Information and Stock
Center National Institute of Agrobiological Resources, Tsukuba, Japan.
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HGMP-RC
Biological Resources, including mouse and rat, UK
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